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Alnylam Pharmaceuticals Inc stock is traded at $269.11, with a volume of 101.36K. It is down -0.72% in the last 24 hours and up +9.04% over the past month. Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
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Previous Close:
$271.02
Open:
$270.51
24h Volume:
101.36K
Relative Volume:
0.14
Market Cap:
$35.08B
Revenue:
$2.25B
Net Income/Loss:
$-278.16M
P/E Ratio:
-124.01
EPS:
-2.17
Net Cash Flow:
$-42.59M
1W Performance:
-5.04%
1M Performance:
+9.04%
6M Performance:
-2.13%
1Y Performance:
+80.03%
1-Day Range:
Value
$264.88
$270.51
1-Week Range:
Value
$264.13
$300.90
52-Week Range:
Value
$141.97
$304.39

Alnylam Pharmaceuticals Inc Stock (ALNY) Company Profile

Name
Name
Alnylam Pharmaceuticals Inc
Name
Phone
(617) 551-8200
Name
Address
675 WEST KENDALL STREET, CAMBRIDGE, MA
Name
Employee
2,230
Name
Twitter
@alnylam
Name
Next Earnings Date
2024-10-31
Name
Latest SEC Filings
Name
ALNY's Discussions on Twitter

Compare ALNY with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
269.13 35.08B 2.25B -278.16M -42.59M -2.17
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
501.01 131.41B 11.02B -535.60M -978.00M -2.20
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
633.56 72.26B 14.20B 4.41B 3.54B 38.28
Biotechnology icon
ARGX
Argen X Se Adr
594.88 36.20B 2.19B 833.04M -1.28B 12.71
Biotechnology icon
ONC
Beigene Ltd Adr
273.83 28.24B 3.81B -644.79M -669.77M -6.24

Alnylam Pharmaceuticals Inc Stock (ALNY) Upgrades & Downgrades

Date Action Analyst Rating Change
Mar-24-25 Upgrade JP Morgan Neutral → Overweight
Nov-12-24 Downgrade Wolfe Research Peer Perform → Underperform
Oct-16-24 Initiated Scotiabank Sector Outperform
Aug-16-24 Upgrade Goldman Neutral → Buy
Feb-16-24 Downgrade Goldman Buy → Neutral
Feb-15-24 Initiated Wolfe Research Peer Perform
Dec-08-23 Initiated Wells Fargo Equal Weight
Oct-11-23 Downgrade Oppenheimer Outperform → Perform
Sep-29-23 Initiated Raymond James Outperform
May-05-23 Upgrade BMO Capital Markets Market Perform → Outperform
Apr-26-23 Initiated SMBC Nikko Neutral
Mar-21-23 Initiated Bernstein Outperform
Jan-18-23 Initiated Canaccord Genuity Buy
Sep-09-22 Resumed Morgan Stanley Equal-Weight
Jul-13-22 Initiated Cantor Fitzgerald Neutral
Jun-27-22 Downgrade Guggenheim Buy → Neutral
Jun-07-22 Initiated William Blair Outperform
Apr-25-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Mar-01-22 Initiated Citigroup Buy
Feb-03-22 Upgrade Guggenheim Neutral → Buy
Jan-03-22 Upgrade Piper Sandler Neutral → Overweight
Nov-22-21 Upgrade Goldman Neutral → Buy
Nov-22-21 Upgrade RBC Capital Mkts Sector Perform → Outperform
Nov-01-21 Upgrade Oppenheimer Perform → Outperform
Oct-04-21 Upgrade UBS Neutral → Buy
Aug-04-21 Downgrade Piper Sandler Overweight → Neutral
Feb-22-21 Downgrade Guggenheim Buy → Neutral
Feb-12-21 Downgrade Citigroup Buy → Neutral
Feb-12-21 Reiterated H.C. Wainwright Buy
Jan-25-21 Downgrade BMO Capital Markets Outperform → Market Perform
Sep-30-20 Resumed Berenberg Hold
Sep-08-20 Initiated Citigroup Buy
Aug-11-20 Downgrade Oppenheimer Outperform → Perform
May-13-20 Initiated RBC Capital Mkts Sector Perform
May-07-20 Downgrade JP Morgan Overweight → Neutral
Apr-24-20 Resumed Evercore ISI Outperform
Mar-19-20 Initiated Berenberg Buy
Dec-19-19 Reiterated Chardan Capital Markets Buy
Nov-20-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
May-23-19 Resumed Goldman Neutral
Apr-12-19 Initiated Evercore ISI Outperform
Mar-06-19 Upgrade Evercore ISI In-line → Outperform
Mar-05-19 Upgrade Morgan Stanley Equal-Weight → Overweight
Jan-23-19 Initiated UBS Neutral
Oct-01-18 Initiated Cantor Fitzgerald Overweight
Aug-13-18 Reiterated Stifel Buy
Aug-07-18 Upgrade Stifel Hold → Buy
May-04-18 Reiterated Stifel Hold
Mar-28-18 Initiated Evercore ISI In-line
View All

Alnylam Pharmaceuticals Inc Stock (ALNY) Latest News

pulisher
Mar 27, 2025

Alnylam and Tekmira Restructure Relationship and Settle All Litigation - AOL

Mar 27, 2025
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Mar 26, 2025

Alnylam CEO's compensation package continues to grow - NBC Boston

Mar 26, 2025
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Mar 26, 2025

Alnylam CEO’s compensation package continues to grow - The Business Journals

Mar 26, 2025
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Mar 26, 2025

Biotech Stock Roundup: SAVA Dives on Setback, ALNY Up on Update & More - Yahoo Finance

Mar 26, 2025
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Mar 26, 2025

Transthyretin Amyloidosis Treatment Market Detailed In New - openPR

Mar 26, 2025
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Mar 25, 2025

Alnylam Pharmaceuticals director David Pyott sells $2.2 million in stock By Investing.com - Investing.com Australia

Mar 25, 2025
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Mar 25, 2025

Alnylam (ALNY) Surges 11.8%: Is This an Indication of Further Gains? - MSN

Mar 25, 2025
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Mar 25, 2025

Alnylam Pharmaceuticals director David Pyott sells $2.2 million in stock - Investing.com India

Mar 25, 2025
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Mar 25, 2025

Alnylam Pharmaceuticals’ SWOT analysis: stock poised for growth in expanding ATTR-CM market - Investing.com India

Mar 25, 2025
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Mar 24, 2025

FDA approves new drug to treat protein buildup in the heart - UPI News

Mar 24, 2025
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Mar 24, 2025

Alnylam Pharmaceuticals Presents 'Convincing Multi-Billion Dollar Opportunity': Analyst Upgrades Stock - Benzinga

Mar 24, 2025
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Mar 24, 2025

FDA OKs Amvuttra To Treat Heart Conditions - The Daily Courier

Mar 24, 2025
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Mar 24, 2025

RBC Capital holds $330 target on Alnylam stock post-Amvuttra approval - Investing.com

Mar 24, 2025
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Mar 24, 2025

Alnylam Pharmaceuticals Stock (ALNY): Innovative Treatment for ATTR Amyloidosis - Value the Markets

Mar 24, 2025
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Mar 24, 2025

Carnival To Rally Around 48%? Here Are 10 Top Analyst Forecasts For Monday - Benzinga

Mar 24, 2025
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Mar 24, 2025

JPMorgan Upgrades Alnylam Pharmaceuticals to Overweight From Neutral, Adjusts Price Target to $328 From $280 - Marketscreener.com

Mar 24, 2025
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Mar 24, 2025

Alnylam Pharmaceuticals, Beacon Roofing, Liberty Energy - TradingView

Mar 24, 2025
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Mar 24, 2025

JPMorgan raises Alnylam stock rating, lifts target to $328 - Investing.com

Mar 24, 2025
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Mar 24, 2025

Alnylam Heart Drug Approval Sets Up Challenge With Pfizer - MSN

Mar 24, 2025
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Mar 23, 2025

Alnylam Pharmaceuticals (NasdaqGS:ALNY) Sees 17% Weekly Gain As Vutrisiran Faces FDA Decision - Simply Wall St

Mar 23, 2025
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Mar 23, 2025

Robinhood, Roku And Shopify Are Among Top 10 Large-Cap Gainers Last Week (Mar 17-Mar 21): Are The Others In Your Portfolio? - Benzinga

Mar 23, 2025
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Mar 22, 2025

Alnylam Wins Expanded Heart Drug Approval, Challenging Pfizer - MSN

Mar 22, 2025
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Mar 22, 2025

Alnylam price target raised to $338 from $300 at Scotiabank - Yahoo Finance

Mar 22, 2025
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Mar 22, 2025

Alnylam Pharmaceuticals’ SWOT analysis: RNAi leader’s stock poised for growth in ATTR-CM market - Investing.com

Mar 22, 2025
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Mar 22, 2025

Teenager dies after receiving Sarepta therapy; Immunovant gets Phase 3 win, but shifts focus; Alnylam’s big moment; and more - Endpoints News

Mar 22, 2025
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Mar 21, 2025

Alnylam Stock Jumps After the FDA Approves Its Heart Drug - The Wall Street Journal

Mar 21, 2025
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Mar 21, 2025

Alnylam Pharmaceuticals Ready To Go With Its Next Blockbuster (NASDAQ:ALNY) - Seeking Alpha

Mar 21, 2025
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Mar 21, 2025

U.S. Markets Moved Upward Friday; Alnylam Pharmaceuticals Climbed Highest - Barron's

Mar 21, 2025
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Mar 21, 2025

Alnylam: US Approval of Amvuttra in ATTR-CM Significantly Expands Addressable Patient Population - Morningstar

Mar 21, 2025
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Mar 21, 2025

Alnylam hopes its broad ATTR-CM label can give Amvuttra an edge in heart disease - Endpoints News

Mar 21, 2025
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Mar 21, 2025

Buy, Sell, Or Hold Alnylam Stock At $280? - Forbes

Mar 21, 2025
pulisher
Mar 21, 2025

Check Out What Whales Are Doing With ALNY - Benzinga

Mar 21, 2025
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Mar 21, 2025

Alnylam challenges Pfizer and BridgeBio with FDA nod for ATTR-CM drug - Yahoo Finance

Mar 21, 2025
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Mar 21, 2025

Alnylam Pharma Stock (ALNY) Rockets on FDA Drug Approval - TipRanks

Mar 21, 2025
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Mar 21, 2025

Alnylam Drug Approval Brings Cardiomyopathy Competition to Pfizer, BridgeBio Pharma - MedCity News

Mar 21, 2025
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Mar 21, 2025

Alnylam Gets FDA Nod for Expanded Use of Amvuttra in Cardiomyopathy - TradingView

Mar 21, 2025
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Mar 21, 2025

Alnylam jumps as expanded US approval for heart disease drug fuels growth prospects - MSN

Mar 21, 2025
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Mar 21, 2025

Alnylam prices heart drug at premium to rivals - BioPharma Dive

Mar 21, 2025
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Mar 21, 2025

Alnylam Expanded Heart Drug Approval Sets Up Pfizer Challenge - MSN

Mar 21, 2025
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Mar 21, 2025

Alnylam's Amvuttra Gains Expanded US Approval for Heart ConditionNews and Statistics - IndexBox, Inc.

Mar 21, 2025
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Mar 21, 2025

BofA Securities Raises Price Target on Alnylam Pharmaceuticals to $325 From $302, Keeps Buy Rating - Marketscreener.com

Mar 21, 2025
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Mar 21, 2025

Alnylam Pharmaceuticals Shares Rise After Receipt of US FDA Approval for ATTR-CM Drug - Marketscreener.com

Mar 21, 2025
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Mar 21, 2025

Alnylam's Amvuttra Secures FDA Approval For Expanded Use For Rare Heart Disease, Stock Jumps - Benzinga

Mar 21, 2025
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Mar 21, 2025

Sector Update: Health Care -March 21, 2025 at 09:20 am EDT - Marketscreener.com

Mar 21, 2025
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Mar 21, 2025

Sector Update: Health Care - TradingView

Mar 21, 2025
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Mar 21, 2025

RBC Adjusts Price Target on Alnylam Pharmaceuticals to $330 From $310, Maintains Outperform Rating - Marketscreener.com

Mar 21, 2025
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Mar 21, 2025

Alnylam scores a first with FDA nod for Amvuttra in ATTR-CM - The Pharma Letter

Mar 21, 2025
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Mar 21, 2025

Alnylam shares rise on expanded heart drug approval -March 21, 2025 at 07:32 am EDT - Marketscreener.com

Mar 21, 2025
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Mar 21, 2025

Alnylam stock rises after FDA nod for AMVUTTRA By Investing.com - Investing.com Canada

Mar 21, 2025
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Mar 21, 2025

Alnylam joins three-way contest in ATTR cardiomyopathy - pharmaphorum

Mar 21, 2025
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Mar 21, 2025

Alnylam’s SWOT analysis: biotechnology stock poised for growth amid ATTR-CM market expansion - Investing.com

Mar 21, 2025

Alnylam Pharmaceuticals Inc Stock (ALNY) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Alnylam Pharmaceuticals Inc Stock (ALNY) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
Garg Pushkal
CMO & EVP Dev & Med Affairs
Mar 24 '25
Sale
300.00
5,445
1,633,500
20,221
Garg Pushkal
CMO & EVP Dev & Med Affairs
Mar 21 '25
Sale
285.00
4,321
1,231,485
20,221
PYOTT DAVID E I
Director
Mar 24 '25
Option Exercise
88.95
7,440
661,788
7,576
PYOTT DAVID E I
Director
Mar 24 '25
Sale
299.00
7,440
2,224,560
136
$594.71
price up icon 0.21%
biotechnology ONC
$268.90
price up icon 7.38%
$95.34
price down icon 0.02%
$20.64
price up icon 3.37%
$31.50
price up icon 1.05%
Cap:     |  Volume (24h):