22.27
price up icon1.69%   0.37
after-market After Hours: 22.27
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Spyre Therapeutics Inc stock is traded at $22.27, with a volume of 1.24M. It is up +1.69% in the last 24 hours and down -1.20% over the past month. Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. A range of pharmaceutical options to address IBD exists, including anti-inflammatory drugs, immunosuppressants, and biologics.
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Previous Close:
$21.90
Open:
$22.13
24h Volume:
1.24M
Relative Volume:
2.16
Market Cap:
$1.34B
Revenue:
$1.23M
Net Income/Loss:
$-214.90M
P/E Ratio:
-5.4025
EPS:
-4.1222
Net Cash Flow:
$-151.25M
1W Performance:
+2.11%
1M Performance:
-1.20%
6M Performance:
-22.46%
1Y Performance:
-19.31%
1-Day Range:
Value
$21.79
$22.74
1-Week Range:
Value
$20.25
$22.81
52-Week Range:
Value
$20.07
$47.97

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Name
Spyre Therapeutics Inc
Name
Phone
(617) 651-5940
Name
Address
221 CRESCENT STREET, WALTHAM
Name
Employee
60
Name
Twitter
Name
Next Earnings Date
2024-11-07
Name
Latest SEC Filings
Name
SYRE's Discussions on Twitter

Compare SYRE with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SYRE
Spyre Therapeutics Inc
22.27 1.34B 1.23M -214.90M -151.25M -4.1222
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
438.40 112.90B 10.63B -479.80M -1.35B -1.99
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
683.08 75.06B 13.85B 4.65B 3.32B 40.41
Biotechnology icon
ARGX
Argen X Se Adr
665.68 40.45B 1.86B -40.29M -1.28B -0.85
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
277.16 35.75B 2.09B -332.26M 16.06M -2.62
Biotechnology icon
BNTX
Biontech Se Adr
120.88 28.98B 3.30B -501.07M 1.03B -2.1146

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-04-24 Initiated Wedbush Outperform
Jul-16-24 Initiated Evercore ISI Outperform
May-02-24 Initiated Robert W. Baird Outperform
Mar-01-24 Upgrade Wells Fargo Equal Weight → Overweight
Dec-20-23 Initiated BTIG Research Buy
Dec-11-23 Initiated Guggenheim Buy
Dec-11-23 Initiated Jefferies Buy
May-04-20 Initiated Piper Sandler Overweight
Mar-21-19 Initiated JP Morgan Overweight
Sep-04-18 Downgrade Wells Fargo Outperform → Market Perform
Apr-24-18 Initiated Evercore ISI Outperform
Mar-14-18 Reiterated Needham Buy
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Spyre Therapeutics Inc Stock (SYRE) Latest News

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Jan 26, 2025

JPMorgan Chase & Co. Has $867,000 Stake in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Jan 26, 2025
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Jan 26, 2025

Assenagon Asset Management S.A. Has $527,000 Stock Holdings in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Jan 26, 2025
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Jan 26, 2025

Assenagon Asset Management S.A. Cuts Stock Position in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Jan 26, 2025
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Jan 26, 2025

Analysts Set Spyre Therapeutics, Inc. (NASDAQ:SYRE) Target Price at $54.83 - Defense World

Jan 26, 2025
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Jan 23, 2025

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Given Consensus Rating of "Buy" by Analysts - MarketBeat

Jan 23, 2025
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Jan 22, 2025

Spyre Therapeutics (NASDAQ:SYRE) Shares Up 9.4%Time to Buy? - MarketBeat

Jan 22, 2025
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Jan 21, 2025

SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Spyre Therapeutics, Inc.SYRE - PR Newswire

Jan 21, 2025
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Jan 17, 2025

Spyre Therapeutics (NASDAQ:SYRE) Stock Price Down 5.3%What's Next? - MarketBeat

Jan 17, 2025
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Jan 17, 2025

Lifesci Capital Has Positive Outlook of SYRE FY2024 Earnings - Defense World

Jan 17, 2025
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Jan 16, 2025

FY2024 EPS Forecast for Spyre Therapeutics Lifted by Analyst - MarketBeat

Jan 16, 2025
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Jan 15, 2025

Get Caught Trying - Audacy

Jan 15, 2025
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Jan 14, 2025

Spyre Therapeutics (NASDAQ:SYRE) Given Outperform Rating at Wedbush - Defense World

Jan 14, 2025
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Jan 13, 2025

Spyre Therapeutics (NASDAQ:SYRE) Given "Outperform" Rating at Wedbush - MarketBeat

Jan 13, 2025
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Jan 13, 2025

Spyre Therapeutics Highlights 2025 Priorities and Robust Pipeline of Upcoming Clinical Readouts - PR Newswire

Jan 13, 2025
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Jan 10, 2025

Spyre Therapeutics (NASDAQ:SYRE) Trading Down 9.2%Here's Why - MarketBeat

Jan 10, 2025
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Jan 07, 2025

Spyre Therapeutics (NASDAQ:SYRE) Sees Unusually-High Trading VolumeHere's What Happened - MarketBeat

Jan 07, 2025
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Jan 05, 2025

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Shares Acquired by Jane Street Group LLC - Defense World

Jan 05, 2025
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Jan 03, 2025

Spyre Therapeutics Awards Key Employee Stock Options at $24.35 with 10-Year Term - StockTitan

Jan 03, 2025
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Jan 02, 2025

Spyre Therapeutics Announces Grants of Inducement Awards - PR Newswire

Jan 02, 2025
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Jan 01, 2025

Brokerages Set Spyre Therapeutics, Inc. (NASDAQ:SYRE) Price Target at $51.50 - Defense World

Jan 01, 2025
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Dec 29, 2024

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Given Consensus Recommendation of "Buy" by Analysts - MarketBeat

Dec 29, 2024
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Dec 27, 2024

Geode Capital Management LLC Has $26.21 Million Stake in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Dec 27, 2024
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Dec 27, 2024

Geode Capital Management LLC Purchases 125,214 Shares of Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Dec 27, 2024
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Dec 25, 2024

Contrasting Spyre Therapeutics (NASDAQ:SYRE) & Generation Bio (NASDAQ:GBIO) - Defense World

Dec 25, 2024
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Dec 24, 2024

Spyre Therapeutics (NASDAQ:SYRE) Shares Down 2.5%Here's Why - MarketBeat

Dec 24, 2024
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Dec 24, 2024

Barclays PLC Buys 41,424 Shares of Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Dec 24, 2024
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Dec 24, 2024

Barclays PLC Boosts Stock Position in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Dec 24, 2024
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Dec 23, 2024

Spyre Therapeutics is Now Oversold (SYRE) - Nasdaq

Dec 23, 2024
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Dec 20, 2024

State Street Corp Buys 131,896 Shares of Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Dec 20, 2024
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Dec 20, 2024

UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Sells 3,680 Shares of Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Dec 20, 2024
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Dec 18, 2024

Spyre Therapeutics Added to the Nasdaq Biotechnology Index - PR Newswire

Dec 18, 2024
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Dec 17, 2024

Evercore ISI Group Initiates Coverage of Spyre Therapeutics (SYRE) with Outperform Recommendation - MSN

Dec 17, 2024
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Dec 16, 2024

Jones Trading Initiates Coverage of Spyre Therapeutics (SYRE) with Hold Recommendation - MSN

Dec 16, 2024
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Dec 12, 2024

The Manufacturers Life Insurance Company Has $1.28 Million Holdings in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Dec 12, 2024
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Dec 12, 2024

Spyre Therapeutics: Different Name, Same Tune (NASDAQ:SYRE) - Seeking Alpha

Dec 12, 2024
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Dec 12, 2024

Wellington Management Group LLP Has $44.33 Million Stock Position in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Dec 12, 2024
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Dec 10, 2024

Charles Schwab Investment Management Inc. Has $9.80 Million Holdings in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Dec 10, 2024
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Dec 07, 2024

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Shares Bought by Janus Henderson Group PLC - MarketBeat

Dec 07, 2024
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Dec 04, 2024

61,256 Shares in Spyre Therapeutics, Inc. (NASDAQ:SYRE) Purchased by Cinctive Capital Management LP - MarketBeat

Dec 04, 2024
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Dec 04, 2024

Analysts Set Spyre Therapeutics, Inc. (NASDAQ:SYRE) PT at $48.57 - MarketBeat

Dec 04, 2024
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Dec 03, 2024

SPYRE ALERT: Bragar Eagel & Squire, P.C. is Investigating - GlobeNewswire

Dec 03, 2024
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Dec 03, 2024

Spyre Therapeutics begins dosing subjects in Phase I trials of anti-TL1A antibodies - Yahoo Finance

Dec 03, 2024
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Dec 03, 2024

Spyre begins Phase 1 trials for new IBD treatments By Investing.com - Investing.com Canada

Dec 03, 2024
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Dec 03, 2024

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Shares Bought by Fmr LLC - MarketBeat

Dec 03, 2024
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Dec 02, 2024

Spyre Therapeutics Announces First Participants Dosed in Phase 1 Trials of Novel Half-life Extended Anti-TL1A Antibodies - PR Newswire

Dec 02, 2024
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Dec 01, 2024

Walleye Capital LLC Increases Stock Holdings in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Dec 01, 2024

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$352.30
price down icon 5.49%
$41.04
price up icon 0.79%
$22.36
price up icon 3.33%
$5.41
price up icon 3.84%
biotechnology ONC
$226.89
price up icon 0.08%
$120.88
price down icon 0.23%
Cap:     |  Volume (24h):