18.38
price down icon6.06%   -1.3214
 
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Spyre Therapeutics Inc stock is traded at $18.38, with a volume of 133.89K. It is down -6.06% in the last 24 hours and down -19.19% over the past month. Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. A range of pharmaceutical options to address IBD exists, including anti-inflammatory drugs, immunosuppressants, and biologics.
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Previous Close:
$19.70
Open:
$19.96
24h Volume:
133.89K
Relative Volume:
0.24
Market Cap:
$1.19B
Revenue:
$1.23M
Net Income/Loss:
$-214.90M
P/E Ratio:
-4.4585
EPS:
-4.1222
Net Cash Flow:
$-151.25M
1W Performance:
-12.95%
1M Performance:
-19.19%
6M Performance:
-30.43%
1Y Performance:
-38.11%
1-Day Range:
Value
$18.30
$20.00
1-Week Range:
Value
$18.26
$21.50
52-Week Range:
Value
$18.26
$47.97

Spyre Therapeutics Inc Stock (SYRE) Company Profile

Name
Name
Spyre Therapeutics Inc
Name
Phone
(617) 651-5940
Name
Address
221 CRESCENT STREET, WALTHAM
Name
Employee
60
Name
Twitter
Name
Next Earnings Date
2024-11-07
Name
Latest SEC Filings
Name
SYRE's Discussions on Twitter

Compare SYRE with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
SYRE
Spyre Therapeutics Inc
18.38 1.19B 1.23M -214.90M -151.25M -4.1222
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
488.70 124.35B 11.02B -535.60M -978.00M -2.20
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
689.50 75.07B 14.20B 4.41B 3.54B 38.28
Biotechnology icon
ARGX
Argen X Se Adr
634.75 37.96B 2.19B 833.04M -1.28B 12.71
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
242.95 31.79B 2.25B -278.16M -42.59M -2.17
Biotechnology icon
BNTX
Biontech Se Adr
112.86 27.34B 3.30B -501.07M 1.03B -2.1146

Spyre Therapeutics Inc Stock (SYRE) Upgrades & Downgrades

Date Action Analyst Rating Change
Sep-04-24 Initiated Wedbush Outperform
Jul-16-24 Initiated Evercore ISI Outperform
May-02-24 Initiated Robert W. Baird Outperform
Mar-01-24 Upgrade Wells Fargo Equal Weight → Overweight
Dec-20-23 Initiated BTIG Research Buy
Dec-11-23 Initiated Guggenheim Buy
Dec-11-23 Initiated Jefferies Buy
May-04-20 Initiated Piper Sandler Overweight
Mar-21-19 Initiated JP Morgan Overweight
Sep-04-18 Downgrade Wells Fargo Outperform → Market Perform
Apr-24-18 Initiated Evercore ISI Outperform
Mar-14-18 Reiterated Needham Buy
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Spyre Therapeutics Inc Stock (SYRE) Latest News

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Mar 02, 2025

Spyre Therapeutics (NASDAQ:SYRE) Trading 6.6% Higher After Strong Earnings - Defense World

Mar 02, 2025
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Mar 01, 2025

Spyre Therapeutics Faces Compliance Hurdles After Transition from Smaller Reporting Company Status - MSN

Mar 01, 2025
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Feb 28, 2025

Spyre Therapeutics (NASDAQ:SYRE) Posts Earnings Results, Beats Expectations By $0.08 EPS - MarketBeat

Feb 28, 2025
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Feb 28, 2025

Buy Rating for Spyre Therapeutics Driven by Promising Drug Development and Strong Financial Position - TipRanks

Feb 28, 2025
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Feb 28, 2025

Decoding Spyre Therapeutics Inc (SYRE): A Strategic SWOT Insight - GuruFocus.com

Feb 28, 2025
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Feb 28, 2025

Spyre Therapeutics: Q4 Earnings Snapshot - The Washington Post

Feb 28, 2025
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Feb 27, 2025

Spyre Therapeutics Reports Strong Progress and Financial Stability - TipRanks

Feb 27, 2025
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Feb 27, 2025

Spyre Therapeutics reports Q4 EPS (81c), consensus (94c) - TipRanks

Feb 27, 2025
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Feb 27, 2025

Spyre Therapeutics Inc reports results for the quarter ended December 31Earnings Summary - TradingView

Feb 27, 2025
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Feb 27, 2025

Spyre Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update - PR Newswire

Feb 27, 2025
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Feb 27, 2025

Spyre Therapeutics (NASDAQ:SYRE) Hits New 1-Year LowTime to Sell? - MarketBeat

Feb 27, 2025
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Feb 27, 2025

Spyre Therapeutics (SYRE) Projected to Post Earnings on Thursday - Defense World

Feb 27, 2025
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Feb 26, 2025

Recent Insider Activity Could Benefit Spyre Therapeutics Inc (SYRE) - Knox Daily

Feb 26, 2025
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Feb 25, 2025

SYRE Stock Touches 52-Week Low at $20.24 Amid Market Challenges - Investing.com

Feb 25, 2025
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Feb 25, 2025

IBD-Focused Spyre Therapeutics Sets Investor Conference Schedule for MarchWhat to Expect - StockTitan

Feb 25, 2025
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Feb 25, 2025

Spyre Therapeutics (NASDAQ:SYRE) Shares Down 6.7%Time to Sell? - MarketBeat

Feb 25, 2025
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Feb 21, 2025

Spyre Therapeutics (NASDAQ:SYRE) Upgraded at The Goldman Sachs Group - Defense World

Feb 21, 2025
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Feb 20, 2025

Spyre Therapeutics, Inc. (SYRE) Investigation: Bronstein, Gewirtz & Grossman, LLC Encourages Stockholders to Contact the Firm to Learn More About the Investigation - ACCESS Newswire

Feb 20, 2025
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Feb 19, 2025

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Given Consensus Rating of "Buy" by Analysts - MarketBeat

Feb 19, 2025
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Feb 19, 2025

Can This Novel Dual-Action IBD Treatment Transform Patient Care? New Data Reveals Promising Results - StockTitan

Feb 19, 2025
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Feb 17, 2025

Spyre Therapeutics, Inc. (NASDAQ:SYRE) Given Consensus Recommendation of “Buy” by Analysts - Defense World

Feb 17, 2025
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Feb 15, 2025

1,955 Shares in Spyre Therapeutics, Inc. (NASDAQ:SYRE) Acquired by Mirae Asset Global Investments Co. Ltd. - Defense World

Feb 15, 2025
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Feb 12, 2025

InvestingPro Fair Value analysis proves accurate on Spyre Therapeutics call - MSN

Feb 12, 2025
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Feb 10, 2025

Can Spyre Therapeutics (SYRE) Climb 158.85% to Reach the Level Wall Street Analysts Expect? - MSN

Feb 10, 2025
pulisher
Feb 10, 2025

InvestingPro Fair Value analysis proves accurate on Spyre Therapeutics call By Investing.com - Investing.com

Feb 10, 2025
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Feb 07, 2025

Spyre (SYRE) Unveils Strategic Talent Retention Plan: 35K Options with 10-Year Window - StockTitan

Feb 07, 2025
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Feb 06, 2025

China Universal Asset Management Co. Ltd. Makes New Investment in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Feb 06, 2025
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Feb 05, 2025

SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Spyre Therapeutics, Inc.SYRE - cnhinews.com

Feb 05, 2025
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Feb 05, 2025

A company insider recently sold 6,700 shares of Spyre Therapeutics Inc [SYRE]. Should You also Consider to Sale? - Knox Daily

Feb 05, 2025
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Feb 05, 2025

Financial Analysis: Spyre Therapeutics Inc (SYRE)’s Ratios Unveil Key Insights - The Dwinnex

Feb 05, 2025
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Feb 04, 2025

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Spyre Therapeutics, Inc.SYRE - PR Newswire

Feb 04, 2025
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Feb 04, 2025

Spyre Therapeutics Inc (SYRE) stock analysis: A comprehensive overview - US Post News

Feb 04, 2025
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Feb 04, 2025

Oruka Therapeutics initiated with an Outperform at Wolfe Research - MSN

Feb 04, 2025
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Feb 03, 2025

Spyre Therapeutics Announces Grants of Inducement Awards - PR Newswire

Feb 03, 2025
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Jan 26, 2025

JPMorgan Chase & Co. Has $867,000 Stake in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Jan 26, 2025
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Jan 26, 2025

Assenagon Asset Management S.A. Has $527,000 Stock Holdings in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - Defense World

Jan 26, 2025
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Jan 26, 2025

Assenagon Asset Management S.A. Cuts Stock Position in Spyre Therapeutics, Inc. (NASDAQ:SYRE) - MarketBeat

Jan 26, 2025
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Jan 26, 2025

Analysts Set Spyre Therapeutics, Inc. (NASDAQ:SYRE) Target Price at $54.83 - Defense World

Jan 26, 2025
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Jan 22, 2025

Spyre Therapeutics (NASDAQ:SYRE) Shares Up 9.4%Time to Buy? - MarketBeat

Jan 22, 2025
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Jan 17, 2025

Spyre Therapeutics (NASDAQ:SYRE) Stock Price Down 5.3%What's Next? - MarketBeat

Jan 17, 2025
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Jan 17, 2025

Lifesci Capital Has Positive Outlook of SYRE FY2024 Earnings - Defense World

Jan 17, 2025
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Jan 16, 2025

FY2024 EPS Forecast for Spyre Therapeutics Lifted by Analyst - MarketBeat

Jan 16, 2025
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Jan 15, 2025

Get Caught Trying - Audacy

Jan 15, 2025
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Jan 14, 2025

Spyre Therapeutics (NASDAQ:SYRE) Given Outperform Rating at Wedbush - Defense World

Jan 14, 2025
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Jan 13, 2025

Spyre Therapeutics (NASDAQ:SYRE) Given "Outperform" Rating at Wedbush - MarketBeat

Jan 13, 2025
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Jan 13, 2025

Spyre Therapeutics Highlights 2025 Priorities and Robust Pipeline of Upcoming Clinical Readouts - PR Newswire

Jan 13, 2025
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Jan 13, 2025

Spyre Therapeutics Unveils Ambitious 2025 Pipeline Plans with $600M Cash Runway Through 2028 - StockTitan

Jan 13, 2025
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Jan 10, 2025

Spyre Therapeutics (NASDAQ:SYRE) Trading Down 9.2%Here's Why - MarketBeat

Jan 10, 2025
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Jan 07, 2025

Spyre Therapeutics (NASDAQ:SYRE) Sees Unusually-High Trading VolumeHere's What Happened - MarketBeat

Jan 07, 2025

Spyre Therapeutics Inc Stock (SYRE) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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$78.82
price down icon 3.23%
$23.07
price up icon 1.68%
$34.02
price up icon 1.11%
$20.07
price down icon 2.46%
biotechnology ONC
$244.35
price down icon 10.01%
$112.86
price down icon 0.06%
Cap:     |  Volume (24h):