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Ionis Pharmaceuticals Inc stock is traded at $33.36, with a volume of 455.38K. It is up +0.49% in the last 24 hours and up +3.80% over the past month. Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.
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Previous Close:
$33.19
Open:
$33.255
24h Volume:
455.38K
Relative Volume:
0.29
Market Cap:
$5.28B
Revenue:
$803.07M
Net Income/Loss:
$-358.81M
P/E Ratio:
-13.67
EPS:
-2.44
Net Cash Flow:
$-374.21M
1W Performance:
+4.59%
1M Performance:
+3.80%
6M Performance:
-29.50%
1Y Performance:
-26.63%
1-Day Range:
Value
$32.87
$33.54
1-Week Range:
Value
$30.99
$33.54
52-Week Range:
Value
$30.23
$52.34

Ionis Pharmaceuticals Inc Stock (IONS) Company Profile

Name
Name
Ionis Pharmaceuticals Inc
Name
Phone
(760) 931-9200
Name
Address
2855 GAZELLE COURT, CARLSBAD, CA
Name
Employee
927
Name
Twitter
@ionispharma
Name
Next Earnings Date
2024-11-06
Name
Latest SEC Filings
Name
IONS's Discussions on Twitter

Compare IONS with other stocks

Stocks Price Market Cap Revenue Net Income Cash Flow EPS
Biotechnology icon
IONS
Ionis Pharmaceuticals Inc
33.37 5.28B 803.07M -358.81M -374.21M -2.44
Biotechnology icon
VRTX
Vertex Pharmaceuticals Inc
489.18 124.35B 11.02B -535.60M -978.00M -2.20
Biotechnology icon
REGN
Regeneron Pharmaceuticals Inc
690.05 75.07B 14.20B 4.41B 3.54B 38.28
Biotechnology icon
ARGX
Argen X Se Adr
636.58 37.96B 2.19B 833.04M -1.28B 12.71
Biotechnology icon
ALNY
Alnylam Pharmaceuticals Inc
243.53 31.79B 2.25B -278.16M -42.59M -2.17
Biotechnology icon
BNTX
Biontech Se Adr
113.23 27.34B 3.30B -501.07M 1.03B -2.1146

Ionis Pharmaceuticals Inc Stock (IONS) Upgrades & Downgrades

Date Action Analyst Rating Change
Aug-02-24 Downgrade BMO Capital Markets Outperform → Market Perform
Jul-24-24 Upgrade Leerink Partners Market Perform → Outperform
Jul-16-24 Resumed Jefferies Buy
Jun-14-24 Upgrade Bernstein Underperform → Mkt Perform
Apr-10-24 Upgrade Wolfe Research Peer Perform → Outperform
Jan-02-24 Upgrade BofA Securities Neutral → Buy
Oct-23-23 Upgrade BofA Securities Underperform → Neutral
Sep-29-23 Initiated Raymond James Strong Buy
Jul-31-23 Upgrade Citigroup Neutral → Buy
Jun-07-23 Resumed Piper Sandler Overweight
May-04-23 Upgrade Citigroup Sell → Neutral
Mar-21-23 Initiated Bernstein Underperform
Dec-21-22 Downgrade Morgan Stanley Overweight → Equal-Weight
Sep-09-22 Resumed Morgan Stanley Overweight
Jul-18-22 Resumed Oppenheimer Outperform
Mar-31-22 Resumed Piper Sandler Overweight
Mar-01-22 Initiated Citigroup Sell
Mar-01-22 Initiated Guggenheim Buy
Feb-01-22 Downgrade BofA Securities Buy → Underperform
Dec-14-21 Upgrade William Blair Mkt Perform → Outperform
May-07-21 Upgrade UBS Sell → Neutral
Mar-01-21 Upgrade Barclays Underweight → Equal Weight
Dec-16-20 Initiated UBS Sell
Dec-15-20 Upgrade Cowen Market Perform → Outperform
Sep-14-20 Resumed JP Morgan Neutral
Sep-02-20 Initiated The Benchmark Company Hold
Jun-01-20 Resumed Oppenheimer Outperform
May-13-20 Initiated RBC Capital Mkts Outperform
Mar-05-20 Initiated Citigroup Buy
Dec-13-19 Initiated Oppenheimer Outperform
Nov-13-19 Initiated BofA/Merrill Buy
Nov-07-19 Downgrade Morgan Stanley Equal-Weight → Underweight
Sep-10-19 Upgrade Bernstein Mkt Perform → Outperform
Aug-08-18 Reiterated Stifel Hold
Aug-07-18 Reiterated Stifel Hold
May-08-18 Downgrade Evercore ISI Outperform → In-line
Oct-06-17 Resumed Goldman Sell
Aug-17-17 Initiated Evercore ISI Outperform
Aug-09-17 Reiterated Stifel Hold
Mar-10-17 Downgrade Goldman Neutral → Sell
Dec-28-16 Reiterated BMO Capital Markets Outperform
Dec-27-16 Reiterated Leerink Partners Mkt Perform
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Ionis Pharmaceuticals Inc Stock (IONS) Latest News

pulisher
Feb 28, 2025

ARK Investment Management LLC Sells 359,009 Shares of Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) - MarketBeat

Feb 28, 2025
pulisher
Feb 28, 2025

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Receives $60.00 Consensus Target Price from Analysts - MarketBeat

Feb 28, 2025
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Feb 28, 2025

Investor Network: Ionis Pharmaceuticals, Inc. to Host Earnings Call - ACCESS Newswire

Feb 28, 2025
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Feb 28, 2025

Ionis' Q4 Earnings and Sales Beat Estimates, Tryngolza Launch in Focus - MSN

Feb 28, 2025
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Feb 28, 2025

FY2026 Earnings Estimate for IONS Issued By Leerink Partnrs - MarketBeat

Feb 28, 2025
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Feb 27, 2025

Intellia: Balancing in vivo risk with validated targets - BioCentury

Feb 27, 2025
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Feb 27, 2025

Ionis Pharmaceuticals, Inc. to Host Earnings Call - ACCESS Newswire

Feb 27, 2025
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Feb 27, 2025

C WorldWide Group Holding A S Has $13.98 Million Stock Holdings in Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) - MarketBeat

Feb 27, 2025
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Feb 26, 2025

Leerink upgrades Ionis to outperform, cites Angelman drug - MSN

Feb 26, 2025
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Feb 25, 2025

Ionis to present at upcoming investor conferences - Post Register

Feb 25, 2025
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Feb 25, 2025

5 Undervalued Stocks That Crushed Q4 Earnings - Morningstar

Feb 25, 2025
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Feb 25, 2025

Ionis Pharmaceuticals’ SWOT analysis: RNA pioneer’s stock faces pivotal year - Investing.com

Feb 25, 2025
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Feb 24, 2025

Ionis Pharmaceuticals EVP Patrick O'Neil sells $39,046 in stock By Investing.com - Investing.com Canada

Feb 24, 2025
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Feb 24, 2025

Ionis Pharmaceuticals Officer Sells Shares - TradingView

Feb 24, 2025
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Feb 24, 2025

The Zacks Analyst Blog Highlights Merck, Sanofi, Regeneron and Ionis - Nasdaq

Feb 24, 2025
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Feb 24, 2025

Ionis Pharmaceuticals (NASDAQ:IONS) Price Target Cut to $45.00 by Analysts at BMO Capital Markets - MarketBeat

Feb 24, 2025
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Feb 23, 2025

Ionis Pharmaceuticals (NASDAQ:IONS) Issues Earnings Results - MarketBeat

Feb 23, 2025
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Feb 22, 2025

Ionis Pharmaceuticals Reports Strong 2024 Results - TipRanks

Feb 22, 2025
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Feb 21, 2025

Ionis Pharmaceuticals targets multibillion-dollar revenue potential with TRYNGOLZA and new launches - MSN

Feb 21, 2025
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Feb 21, 2025

Ionis Pharmaceuticals price target lowered to $60 from $61 at Raymond James - Yahoo Finance

Feb 21, 2025
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Feb 21, 2025

New positive donidalorsen data to be presented at AAAAI/WAO Joint Congress highlight sustained HAE attack rate reduction and disease control - BioSpace

Feb 21, 2025
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Feb 20, 2025

Ionis Earnings: Tryngolza Commercial Launch Underway; Shares Very Undervalued - Morningstar

Feb 20, 2025
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Feb 20, 2025

Ionis posts Q4 beat as revenue base widens - MSN

Feb 20, 2025
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Feb 20, 2025

Ionis Pharmaceuticals price target lowered to $38 from $45 at Stifel - MSN

Feb 20, 2025
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Feb 20, 2025

What Analysts Are Saying About Ionis Pharmaceuticals Stock - Benzinga

Feb 20, 2025
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Feb 20, 2025

Ionis presents new data on HAE drug donidalorsen By Investing.com - Investing.com Nigeria

Feb 20, 2025
pulisher
Feb 20, 2025

BESREMi Achieves Strong Market Growth Amid Rising Demand for Polycythemia Vera Treatment - GlobeNewswire Inc.

Feb 20, 2025
pulisher
Feb 20, 2025

Why Ionis Pharmaceuticals (IONS) Is Among the Most Oversold Healthcare Stocks to Buy Now - Insider Monkey

Feb 20, 2025
pulisher
Feb 20, 2025

Ionis Continues to Expand Its Cardiology and Neurology Portfolio, Supporting Narrow Moat - Morningstar

Feb 20, 2025
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Feb 20, 2025

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Q4 2024 Earnings Call Transcript - Insider Monkey

Feb 20, 2025
pulisher
Feb 20, 2025

Ionis stock target cut to $60 by Raymond James - Investing.com India

Feb 20, 2025
pulisher
Feb 20, 2025

Ionis presents new data on HAE drug donidalorsen - Investing.com

Feb 20, 2025
pulisher
Feb 20, 2025

Ionis Pharmaceuticals Full Year 2024 Earnings: Beats Expectations - Simply Wall St

Feb 20, 2025
pulisher
Feb 20, 2025

Can This New HAE Treatment Transform Patient Care? Key Clinical Data Revealed - StockTitan

Feb 20, 2025
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Feb 20, 2025

Ionis Pharmaceuticals Inc (IONS) Q4 2024 Earnings Call Highlights: Surpassing Revenue ... - Yahoo Finance

Feb 20, 2025
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Feb 20, 2025

Ionis Pharmaceuticals: Q4 Earnings Snapshot - The Advocate

Feb 20, 2025
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Feb 19, 2025

Ionis Pharmaceuticals (IONS) Reports Q4 Earnings: What Key Metrics Have to Say - MSN

Feb 19, 2025
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Feb 19, 2025

Ionis Pharmaceuticals (IONS) Reports Q4 Loss, Tops Revenue Estimates - MSN

Feb 19, 2025
pulisher
Feb 19, 2025

12 Most Oversold Healthcare Stocks to Buy Now - Insider Monkey

Feb 19, 2025
pulisher
Feb 19, 2025

Ionis Pharmaceuticals: Positive Sentiment in Earnings Call - TipRanks

Feb 19, 2025
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Feb 19, 2025

Ionis Pharmaceuticals (NASDAQ:IONS) Stock Quotes, Forecast and News Summary - Benzinga

Feb 19, 2025
pulisher
Feb 19, 2025

Stifel cuts Ionis Pharmaceuticals target to $38, maintains Hold - Investing.com India

Feb 19, 2025
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Feb 19, 2025

Ionis Pharmaceuticals Reports Strong Q4 Earnings After Recent FDA Approval (IONS) - Seeking Alpha

Feb 19, 2025
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Feb 19, 2025

Ionis Pharmaceuticals Q4 Revenue Growth Exceeds Guidance, Forecasts Over $600 Million In 2025 Sales - AOL

Feb 19, 2025
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Feb 19, 2025

Ionis Pharma Beats Expectations for Q4 - MSN

Feb 19, 2025
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Feb 19, 2025

Earnings call transcript: Ionis Pharmaceuticals Q4 2024 surpasses forecasts - Investing.com

Feb 19, 2025
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Feb 19, 2025

Earnings call transcript: Ionis Pharmaceuticals Q4 2024 surpasses forecasts By Investing.com - Investing.com Nigeria

Feb 19, 2025
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Feb 19, 2025

Ionis Pharmaceuticals Reports Fourth Quarter and Full Year 2024 Financial Results - TradingView

Feb 19, 2025
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Feb 19, 2025

Ionis Pharmaceuticals Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits - Quantisnow

Feb 19, 2025
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Feb 19, 2025

Ionis Pharmaceuticals, Inc. Reports Earnings Results for the Fourth Quarter and Full Year Ended December 31, 2024 - Marketscreener.com

Feb 19, 2025
pulisher
Feb 19, 2025

Ionis stock gains on Q4 beat (IONS:NASDAQ) - Seeking Alpha

Feb 19, 2025

Ionis Pharmaceuticals Inc Stock (IONS) Financials Data

Revenue

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Net Income

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Cash Flow

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EPS

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Ionis Pharmaceuticals Inc Stock (IONS) Insider Trading

Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total
O'NEIL PATRICK R.
EVP CLO & General Counsel
Feb 04 '25
Sale
31.62
6,165
194,939
57,452
Monia Brett P
Chief Executive Officer
Feb 04 '25
Sale
31.65
38,843
1,229,463
180,683
$78.98
price down icon 2.93%
$23.11
price up icon 1.81%
$34.05
price up icon 1.25%
$20.27
price down icon 2.22%
biotechnology ONC
$245.74
price down icon 9.54%
$113.23
price up icon 0.28%
Cap:     |  Volume (24h):